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3D structure of Alzheimer's amyloid-β(1–42) fibrils
Alzheimer's disease is the most fatal neurodegenerative disorder wherein the process of amyloid-β (Aβ) amyloidogenesis appears causative. Here, we present the 3D structure of the fibrils comprising Aβ(1–42), which was obtained by using hydrogen-bonding constraints from quenched hydrogen/deuteri...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1297669/ https://ncbi.nlm.nih.gov/pubmed/16293696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506723102 |
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