In vivo demonstration that α-synuclein oligomers are toxic

The aggregation of proteins into oligomers and amyloid fibrils is characteristic of several neurodegenerative diseases, including Parkinson disease (PD). In PD, the process of aggregation of α-synuclein (α-syn) from monomers, via oligomeric intermediates, into amyloid fibrils is considered the disea...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Winner, Beate, Jappelli, Roberto, Maji, Samir K., Desplats, Paula A., Boyer, Leah, Aigner, Stefan, Hetzer, Claudia, Loher, Thomas, Vilar, Marçal, Campioni, Silvia, Tzitzilonis, Christos, Soragni, Alice, Jessberger, Sebastian, Mira, Helena, Consiglio, Antonella, Pham, Emiley, Masliah, Eliezer, Gage, Fred H., Riek, Roland
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053976/
https://ncbi.nlm.nih.gov/pubmed/21325059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100976108
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker