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β–Synuclein occurs in vivo in lipid associated oligomers and forms hetero oligomers with α-synuclein
α-synuclein (αS) and β-synuclein (βS) are homologous proteins implicated in Parkinson’s disease and the related synucleinopathies. While αS is neurotoxic and its aggregation and deposition in Lewy bodies is related to neurodegeneration, βS is considered a potent inhibitor of αS aggregation and toxic...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832289/ https://ncbi.nlm.nih.gov/pubmed/19012742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05776.x |
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