α-Synuclein Oligomers with Broken Helical Conformation Form Lipoprotein Nanoparticles

α-Synuclein (αS) is a membrane-binding protein with sequence similarity to apolipoproteins and other lipid-carrying proteins, which are capable of forming lipid-containing nanoparticles, sometimes referred to as “discs.” Previously, it has been unclear whether αS also possesses this property. Using...

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Bibliografiske detaljer
Main Authors: Varkey, Jobin, Mizuno, Naoko, Hegde, Balachandra G., Cheng, Naiqian, Steven, Alasdair C., Langen, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682563/
https://ncbi.nlm.nih.gov/pubmed/23609437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476697
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