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An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation

Reactive cellular metabolites can modify macromolecules and form adducts known as nonenzymatic covalent modifications (NECMs). The dissection of the mechanisms, regulation, and consequences of NECMs, such as glycation, has been challenging due to the complex and often ambiguous nature of the adducts...

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Publicado en:J Am Chem Soc
Autores principales: Maksimovic, Igor, Zheng, Qingfei, Trujillo, Marissa N., Galligan, James J., David, Yael
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052992/
https://ncbi.nlm.nih.gov/pubmed/32390412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01325
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