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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation

Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete with arginine methyla...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Zheng, Qingfei, Osunsade, Adewola, David, Yael
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319962/
https://ncbi.nlm.nih.gov/pubmed/32591537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17066-y
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