Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen‐induced arthritis

Citrullination of joint proteins by the protein arginine deiminase (PAD) family of enzymes is recognized increasingly as a key process in the pathogenesis of rheumatoid arthritis. This present study was undertaken to explore the efficacy of a novel PAD4‐selective inhibitor, GSK199, in the murine col...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Willis, V. C., Banda, N. K., Cordova, K. N., Chandra, P. E., Robinson, W. H., Cooper, D. C., Lugo, D., Mehta, G., Taylor, S., Tak, P. P., Prinjha, R. K., Lewis, H. D., Holers, V. M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383440/
https://ncbi.nlm.nih.gov/pubmed/28128853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12932
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