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Arginine deiminase: a potential inhibitor of angiogenesis and tumour growth
Hydrolysis of plasma arginine to citrulline by arginine deiminase (ADI) was recently shown to suppress lipopolysaccharide-induced nitric oxide (NO) synthesis. Since arginine is the precursor of NO, and the latter modulates angiogenesis, we explored whether ADI treatment significantly affected tube-l...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394481/ https://ncbi.nlm.nih.gov/pubmed/12942125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601181 |
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