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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete with arginine methyla...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319962/ https://ncbi.nlm.nih.gov/pubmed/32591537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17066-y |
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