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An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation

Reactive cellular metabolites can modify macromolecules and form adducts known as nonenzymatic covalent modifications (NECMs). The dissection of the mechanisms, regulation, and consequences of NECMs, such as glycation, has been challenging due to the complex and often ambiguous nature of the adducts...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Maksimovic, Igor, Zheng, Qingfei, Trujillo, Marissa N., Galligan, James J., David, Yael
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052992/
https://ncbi.nlm.nih.gov/pubmed/32390412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01325
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