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An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation

Reactive cellular metabolites can modify macromolecules and form adducts known as nonenzymatic covalent modifications (NECMs). The dissection of the mechanisms, regulation, and consequences of NECMs, such as glycation, has been challenging due to the complex and often ambiguous nature of the adducts...

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Publicat a:J Am Chem Soc
Autors principals: Maksimovic, Igor, Zheng, Qingfei, Trujillo, Marissa N., Galligan, James J., David, Yael
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052992/
https://ncbi.nlm.nih.gov/pubmed/32390412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01325
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