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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete with arginine methyla...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319962/ https://ncbi.nlm.nih.gov/pubmed/32591537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17066-y |
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