Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐Binding Lectins

Because of the antimicrobial resistance crisis, lectins are considered novel drug targets. Pseudomonas aeruginosa utilizes LecA and LecB in the infection process. Inhibition of both lectins with carbohydrate‐derived molecules can reduce biofilm formation to restore antimicrobial susceptibility. Here...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Main Authors: Kuhaudomlarp, Sakonwan, Siebs, Eike, Shanina, Elena, Topin, Jérémie, Joachim, Ines, da Silva Figueiredo Celestino Gomes, Priscila, Varrot, Annabelle, Rognan, Didier, Rademacher, Christoph, Imberty, Anne, Titz, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048816/
https://ncbi.nlm.nih.gov/pubmed/33314528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013217
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