Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐Binding Lectins

Because of the antimicrobial resistance crisis, lectins are considered novel drug targets. Pseudomonas aeruginosa utilizes LecA and LecB in the infection process. Inhibition of both lectins with carbohydrate‐derived molecules can reduce biofilm formation to restore antimicrobial susceptibility. Here...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Angew Chem Int Ed Engl
Main Authors: Kuhaudomlarp, Sakonwan, Siebs, Eike, Shanina, Elena, Topin, Jérémie, Joachim, Ines, da Silva Figueiredo Celestino Gomes, Priscila, Varrot, Annabelle, Rognan, Didier, Rademacher, Christoph, Imberty, Anne, Titz, Alexander
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048816/
https://ncbi.nlm.nih.gov/pubmed/33314528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013217
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