Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐Binding Lectins

Because of the antimicrobial resistance crisis, lectins are considered novel drug targets. Pseudomonas aeruginosa utilizes LecA and LecB in the infection process. Inhibition of both lectins with carbohydrate‐derived molecules can reduce biofilm formation to restore antimicrobial susceptibility. Here...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Kuhaudomlarp, Sakonwan, Siebs, Eike, Shanina, Elena, Topin, Jérémie, Joachim, Ines, da Silva Figueiredo Celestino Gomes, Priscila, Varrot, Annabelle, Rognan, Didier, Rademacher, Christoph, Imberty, Anne, Titz, Alexander
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048816/
https://ncbi.nlm.nih.gov/pubmed/33314528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013217
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