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Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa

The carbohydrate-binding protein LecA (PA-IL) from Pseudomonas aeruginosa plays an important role in the formation of biofilms in chronic infections. Development of inhibitors to disrupt LecA-mediated biofilms is desired but it is limited to carbohydrate-based ligands. Moreover, discovery of drug-li...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Shanina, Elena, Siebs, Eike, Zhang, Hengxi, Varón Silva, Daniel, Joachim, Ines, Titz, Alexander, Rademacher, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874386/
https://ncbi.nlm.nih.gov/pubmed/32573695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwaa057
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