Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

Biofilm formation by pathogenic bacteria is a hallmark of chronic infections. In many cases, lectins play key roles in establishing biofilms. The pathogen Pseudomonas aeruginosa often exhibiting various drug resistances employs its lectins LecA and LecB as virulence factors and biofilm building bloc...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Wagner, Stefanie, Hauck, Dirk, Hoffmann, Michael, Sommer, Roman, Joachim, Ines, Müller, Rolf, Imberty, Anne, Varrot, Annabelle, Titz, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767747/
https://ncbi.nlm.nih.gov/pubmed/28960731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709368
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