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Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa

[Image: see text] Chronic infections by Pseudomonas aeruginosa are characterized by biofilm formation, which effectively enhances resistance toward antibiotics. Biofilm-specific antibiotic delivery could locally increase drug concentration to break antimicrobial resistance and reduce the drug’s peri...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Med Chem
Prif Awduron: Meiers, Joscha, Zahorska, Eva, Röhrig, Teresa, Hauck, Dirk, Wagner, Stefanie, Titz, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2020
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586336/
https://ncbi.nlm.nih.gov/pubmed/32924479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00856
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