Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic Gram‐negative pathogen with high antibiotic resistance. Its lectin LecB was identified as a virulence factor and is relevant in bacterial adhesion and biofilm formation. Inhibition of LecB with carbohydrate‐based ligands results in a decrease in toxicity an...

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Publicado no:ChemistryOpen
Main Authors: Sommer, Roman, Hauck, Dirk, Varrot, Annabelle, Wagner, Stefanie, Audfray, Aymeric, Prestel, Andreas, Möller, Heiko M., Imberty, Anne, Titz, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906503/
https://ncbi.nlm.nih.gov/pubmed/27308201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201500162
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