Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic Gram‐negative pathogen with high antibiotic resistance. Its lectin LecB was identified as a virulence factor and is relevant in bacterial adhesion and biofilm formation. Inhibition of LecB with carbohydrate‐based ligands results in a decrease in toxicity an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ChemistryOpen
Prif Awduron: Sommer, Roman, Hauck, Dirk, Varrot, Annabelle, Wagner, Stefanie, Audfray, Aymeric, Prestel, Andreas, Möller, Heiko M., Imberty, Anne, Titz, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Full Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906503/
https://ncbi.nlm.nih.gov/pubmed/27308201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201500162
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