The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery

P. aeruginosa causes a substantial number of nosocomial infections and is the leading cause of death of cystic fibrosis patients. This Gram-negative bacterium is highly resistant against antibiotics and further protects itself by forming a biofilm. Moreover, a high genomic variability among clinical...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Sommer, Roman, Wagner, Stefanie, Varrot, Annabelle, Nycholat, Corwin M., Khaledi, Ariane, Häussler, Susanne, Paulson, James C., Imberty, Anne, Titz, Alexander
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2016
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018602/
https://ncbi.nlm.nih.gov/pubmed/30155149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00696e
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