Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic Gram‐negative pathogen with high antibiotic resistance. Its lectin LecB was identified as a virulence factor and is relevant in bacterial adhesion and biofilm formation. Inhibition of LecB with carbohydrate‐based ligands results in a decrease in toxicity an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:ChemistryOpen
Päätekijät: Sommer, Roman, Hauck, Dirk, Varrot, Annabelle, Wagner, Stefanie, Audfray, Aymeric, Prestel, Andreas, Möller, Heiko M., Imberty, Anne, Titz, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2015
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Full Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906503/
https://ncbi.nlm.nih.gov/pubmed/27308201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201500162
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