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Synthesis of σ Receptor Ligands with a Spirocyclic System Connected with a Tetrahydroisoquinoline Moiety via Different Linkers

With the aim to develop new σ(2) receptor ligands, spirocyclic piperidines or cyclohexanamines with 2‐benzopyran and 2‐benzofuran scaffolds were connected to the 6,7‐dimethoxy‐1,2,3,4‐tetrahydroisoquinoline moiety by variable linkers. In addition to flexible alkyl chains, linkers containing an amide...

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Xehetasun bibliografikoak
Argitaratua izan da:ChemMedChem
Egile Nagusiak: Bergkemper, Melanie, Schepmann, Dirk, Wünsch, Bernhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048568/
https://ncbi.nlm.nih.gov/pubmed/33332704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000861
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