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Synthesis and σ receptor affinity of spiro[[2]benzopyran-1,1′-cyclohexanes] with an exocyclic amino moiety in the 3′-position

The main functions of σ(1) receptors include the modulation of release and reuptake of neurotransmitters, the regulation of ion channels and the influence on intracellular signaling through modulation of calcium levels. Due to these properties, σ(1) receptors are interesting drug targets for the tre...

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Publicado en:RSC Med Chem
Main Authors: Kronenberg, Elisabeth, Weber, Frauke, Schepmann, Dirk, Wünsch, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: RSC 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127328/
https://ncbi.nlm.nih.gov/pubmed/34046612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00307g
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