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Synthesis and σ receptor affinity of spiro[[2]benzopyran-1,1′-cyclohexanes] with an exocyclic amino moiety in the 3′-position

The main functions of σ(1) receptors include the modulation of release and reuptake of neurotransmitters, the regulation of ion channels and the influence on intracellular signaling through modulation of calcium levels. Due to these properties, σ(1) receptors are interesting drug targets for the tre...

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Publicat a:RSC Med Chem
Autors principals: Kronenberg, Elisabeth, Weber, Frauke, Schepmann, Dirk, Wünsch, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: RSC 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127328/
https://ncbi.nlm.nih.gov/pubmed/34046612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00307g
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