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Mitochondrial translation deficiency impairs NAD(+)‐mediated lysosomal acidification

Mitochondrial translation dysfunction is associated with neurodegenerative and cardiovascular diseases. Cells eliminate defective mitochondria by the lysosomal machinery via autophagy. The relationship between mitochondrial translation and lysosomal function is unknown. In this study, mitochondrial...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Yagi, Mikako, Toshima, Takahiro, Amamoto, Rie, Do, Yura, Hirai, Haruka, Setoyama, Daiki, Kang, Dongchon, Uchiumi, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047443/
https://ncbi.nlm.nih.gov/pubmed/33528041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105268
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