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Mitochondrial translation deficiency impairs NAD(+)‐mediated lysosomal acidification

Mitochondrial translation dysfunction is associated with neurodegenerative and cardiovascular diseases. Cells eliminate defective mitochondria by the lysosomal machinery via autophagy. The relationship between mitochondrial translation and lysosomal function is unknown. In this study, mitochondrial...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Yagi, Mikako, Toshima, Takahiro, Amamoto, Rie, Do, Yura, Hirai, Haruka, Setoyama, Daiki, Kang, Dongchon, Uchiumi, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047443/
https://ncbi.nlm.nih.gov/pubmed/33528041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105268
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