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Structural basis of nucleosome transcription mediated by Chd1 and FACT

Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone chaperone FACT when the elongation factors Spt4/5 a...

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Détails bibliographiques
Publié dans:Nat Struct Mol Biol
Auteurs principaux: Farnung, Lucas, Ochmann, Moritz, Engeholm, Maik, Cramer, Patrick
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group US 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046669/
https://ncbi.nlm.nih.gov/pubmed/33846633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00578-6
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