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Structural basis of nucleosome transcription mediated by Chd1 and FACT

Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone chaperone FACT when the elongation factors Spt4/5 a...

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Dades bibliogràfiques
Publicat a:Nat Struct Mol Biol
Autors principals: Farnung, Lucas, Ochmann, Moritz, Engeholm, Maik, Cramer, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group US 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046669/
https://ncbi.nlm.nih.gov/pubmed/33846633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00578-6
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