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Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations
Chromatin remodeling plays important roles in gene regulation during development, differentiation and in disease. The chromatin remodeling enzyme CHD4 is a component of the NuRD and ChAHP complexes that are involved in gene repression. Here, we report the cryo-electron microscopy (cryo-EM) structure...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7338049/ https://ncbi.nlm.nih.gov/pubmed/32543371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56178 |
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