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Structural basis of nucleosome transcription mediated by Chd1 and FACT

Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone chaperone FACT when the elongation factors Spt4/5 a...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Farnung, Lucas, Ochmann, Moritz, Engeholm, Maik, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046669/
https://ncbi.nlm.nih.gov/pubmed/33846633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00578-6
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