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Structural basis of nucleosome transcription mediated by Chd1 and FACT

Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone chaperone FACT when the elongation factors Spt4/5 a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Struct Mol Biol
Egile Nagusiak: Farnung, Lucas, Ochmann, Moritz, Engeholm, Maik, Cramer, Patrick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group US 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046669/
https://ncbi.nlm.nih.gov/pubmed/33846633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00578-6
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