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Structure of transcribing RNA polymerase II-nucleosome complex

Transcription of eukaryotic protein-coding genes requires passage of RNA polymerase II (Pol II) through nucleosomes, but it is unclear how this is achieved. Here we report the cryo-EM structure of transcribing Saccharomyces cerevisiae Pol II engaged with a downstream nucleosome core particle at an o...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Farnung, Lucas, Vos, Seychelle M., Cramer, Patrick
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303367/
https://ncbi.nlm.nih.gov/pubmed/30575770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07870-y
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