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Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding

Recognition of histone-modified nucleosomes by specific reader domains underlies the regulation of chromatin-associated processes. Whereas structural studies revealed how reader domains bind modified histone peptides, it is unclear how reader domains interact with modified nucleosomes. Here we repor...

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Wang, Haibo, Farnung, Lucas, Dienemann, Christian, Cramer, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955156/
https://ncbi.nlm.nih.gov/pubmed/31819277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0345-4
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