Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain

BACKGROUND: Recognition of histone modifications by specialized protein domains is a key step in the regulation of DNA-mediated processes like gene transcription. The structural basis of these interactions is usually studied using histone peptide models, neglecting the nucleosomal context. Here, we...

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Autores principales: van Nuland, Rick, van Schaik, Frederik MA, Simonis, Marieke, van Heesch, Sebastiaan, Cuppen, Edwin, Boelens, Rolf, Timmers, HT Marc, van Ingen, Hugo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663649/
https://ncbi.nlm.nih.gov/pubmed/23656834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-12
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