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Mechanistic Investigation of 1,2-Diol Dehydration of Paromamine Catalyzed by the Radical S-adenosyl-l-methionine Enzyme AprD4
AprD4 is a radical S-adenosyl-l-methionine (SAM) enzyme catalyzing C3′-deoxygenation of paromamine to form 4′-oxo-lividamine. It is the only 1,2-diol dehydratase in the radical SAM enzyme superfamily that has been identified and characterized in vitro. The AprD4 catalyzed 1,2-diol dehydration is a k...
Gorde:
| Argitaratua izan da: | J Am Chem Soc |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8045149/ https://ncbi.nlm.nih.gov/pubmed/33784078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c00076 |
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