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Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
Tau and Aβ assemblies of Alzheimer’s disease (AD) can be visualized in living subjects using positron emission tomography (PET). Tau assemblies comprise paired helical and straight filaments (PHFs and SFs). APN-1607 (PM-PBB3) is a recently described PET ligand for AD and other tau proteinopathies. S...
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| Veröffentlicht in: | Acta Neuropathol |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8043864/ https://ncbi.nlm.nih.gov/pubmed/33723967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02294-3 |
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