Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607

Tau and Aβ assemblies of Alzheimer’s disease (AD) can be visualized in living subjects using positron emission tomography (PET). Tau assemblies comprise paired helical and straight filaments (PHFs and SFs). APN-1607 (PM-PBB3) is a recently described PET ligand for AD and other tau proteinopathies. S...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Acta Neuropathol
Päätekijät: Shi, Yang, Murzin, Alexey G., Falcon, Benjamin, Epstein, Alexander, Machin, Jonathan, Tempest, Paul, Newell, Kathy L., Vidal, Ruben, Garringer, Holly J., Sahara, Naruhiko, Higuchi, Makoto, Ghetti, Bernardino, Jang, Ming-Kuei, Scheres, Sjors H. W., Goedert, Michel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2021
Aiheet:
Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043864/
https://ncbi.nlm.nih.gov/pubmed/33723967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02294-3
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