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Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

The ordered assembly of tau protein into abnormal filaments is a defining characteristic of Alzheimer’s disease (AD) and other neurodegenerative disorders. It is not known if the structures of tau filaments vary within, or between, the brains of individuals with AD. We used a combination of electron...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Falcon, Benjamin, Zhang, Wenjuan, Schweighauser, Manuel, Murzin, Alexey G., Vidal, Ruben, Garringer, Holly J., Ghetti, Bernardino, Scheres, Sjors H. W., Goedert, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208733/
https://ncbi.nlm.nih.gov/pubmed/30276465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1914-z
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