Chargement en cours...

Structures of filaments from Pick’s disease reveal a novel tau protein fold

The ordered assembly of tau protein into abnormal filamentous inclusions underlies many human neurodegenerative diseases(1). Tau assemblies appear to spread through specific neural networks in each disease(2), with short filaments having the greatest seeding activity(3). The abundance of tau inclusi...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Falcon, Benjamin, Zhang, Wenjuan, Murzin, Alexey G., Murshudov, Garib, Garringer, Holly J., Vidal, Ruben, Crowther, R. Anthony, Ghetti, Bernardino, Scheres, Sjors H.W., Goedert, Michel
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204212/
https://ncbi.nlm.nih.gov/pubmed/30158706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0454-y
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!