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Structures of filaments from Pick’s disease reveal a novel tau protein fold

The ordered assembly of tau protein into abnormal filamentous inclusions underlies many human neurodegenerative diseases(1). Tau assemblies appear to spread through specific neural networks in each disease(2), with short filaments having the greatest seeding activity(3). The abundance of tau inclusi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Falcon, Benjamin, Zhang, Wenjuan, Murzin, Alexey G., Murshudov, Garib, Garringer, Holly J., Vidal, Ruben, Crowther, R. Anthony, Ghetti, Bernardino, Scheres, Sjors H.W., Goedert, Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204212/
https://ncbi.nlm.nih.gov/pubmed/30158706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0454-y
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