Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases

Assembly of microtubule-associated protein tau into filamentous inclusions underlies a range of neurodegenerative diseases. Tau filaments adopt different conformations in Alzheimer’s and Pick’s diseases. Here, we used cryo- and immuno- electron microscopy to characterise filaments that were assemble...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Zhang, Wenjuan, Falcon, Benjamin, Murzin, Alexey G, Fan, Juan, Crowther, R Anthony, Goedert, Michel, Scheres, Sjors HW
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2019
Konular:
Structural Biology and Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375701/
https://ncbi.nlm.nih.gov/pubmed/30720432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43584
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller