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Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
Assembly of microtubule-associated protein tau into filamentous inclusions underlies a range of neurodegenerative diseases. Tau filaments adopt different conformations in Alzheimer’s and Pick’s diseases. Here, we used cryo- and immuno- electron microscopy to characterise filaments that were assemble...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375701/ https://ncbi.nlm.nih.gov/pubmed/30720432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43584 |
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