Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

The ordered assembly of tau protein into abnormal filaments is a defining characteristic of Alzheimer’s disease (AD) and other neurodegenerative disorders. It is not known if the structures of tau filaments vary within, or between, the brains of individuals with AD. We used a combination of electron...

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Bibliographic Details
Published in:Acta Neuropathol
Main Authors: Falcon, Benjamin, Zhang, Wenjuan, Schweighauser, Manuel, Murzin, Alexey G., Vidal, Ruben, Garringer, Holly J., Ghetti, Bernardino, Scheres, Sjors H. W., Goedert, Michel
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2018
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208733/
https://ncbi.nlm.nih.gov/pubmed/30276465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1914-z
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