Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

The ordered assembly of tau protein into abnormal filaments is a defining characteristic of Alzheimer’s disease (AD) and other neurodegenerative disorders. It is not known if the structures of tau filaments vary within, or between, the brains of individuals with AD. We used a combination of electron...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Falcon, Benjamin, Zhang, Wenjuan, Schweighauser, Manuel, Murzin, Alexey G., Vidal, Ruben, Garringer, Holly J., Ghetti, Bernardino, Scheres, Sjors H. W., Goedert, Michel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2018
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208733/
https://ncbi.nlm.nih.gov/pubmed/30276465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1914-z
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