An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action

The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α(1)-acid glycoprotein (AGP) in AKI and its progression to CKD using AGP KO mice. P...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Watanabe, Hiroshi, Fujimura, Rui, Hiramoto, Yuto, Murata, Ryota, Nishida, Kento, Bi, Jing, Imafuku, Tadashi, Komori, Hisakazu, Maeda, Hitoshi, Mukunoki, Ayumi, Takeo, Toru, Nakagata, Naomi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041882/
https://ncbi.nlm.nih.gov/pubmed/33846468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87217-8
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