Recombinant Long-Acting Thioredoxin Ameliorates AKI to CKD Transition via Modulating Renal Oxidative Stress and Inflammation

An effective strategy is highly desirable for preventing acute kidney injury (AKI) to chronic kidney disease (CKD) transition. Thioredoxin-1 (Trx), a redox-active protein that has anti-oxidative and anti-inflammatory properties, would be a candidate for this but its short half-life limits its clinic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nishida, Kento, Watanabe, Hiroshi, Murata, Ryota, Tokumaru, Kai, Fujimura, Rui, Oshiro, Shun, Nagasaki, Taisei, Miyahisa, Masako, Hiramoto, Yuto, Nosaki, Hiroto, Imafuku, Tadashi, Maeda, Hitoshi, Fukagawa, Masafumi, Maruyama, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199127/
https://ncbi.nlm.nih.gov/pubmed/34070521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115600
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