Systemic and sustained thioredoxin analogue prevents acute kidney injury and its-associated distant organ damage in renal ischemia reperfusion injury mice

The mortality of patients with acute kidney injury (AKI) remains high due to AKI associated-lung injury. An effective strategy for preventing both AKI and AKI-associated lung injury is urgently needed. Thioredoxin-1 (Trx) is a redox-active protein that possesses anti-oxidative, anti-apoptotic and an...

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Publicado no:Sci Rep
Main Authors: Nishida, Kento, Watanabe, Hiroshi, Miyahisa, Masako, Hiramoto, Yuto, Nosaki, Hiroto, Fujimura, Rui, Maeda, Hitoshi, Otagiri, Masaki, Maruyama, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691343/
https://ncbi.nlm.nih.gov/pubmed/33244034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75025-5
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