An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action

The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α(1)-acid glycoprotein (AGP) in AKI and its progression to CKD using AGP KO mice. P...

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Publicat a:Sci Rep
Autors principals: Watanabe, Hiroshi, Fujimura, Rui, Hiramoto, Yuto, Murata, Ryota, Nishida, Kento, Bi, Jing, Imafuku, Tadashi, Komori, Hisakazu, Maeda, Hitoshi, Mukunoki, Ayumi, Takeo, Toru, Nakagata, Naomi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041882/
https://ncbi.nlm.nih.gov/pubmed/33846468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87217-8
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