An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action

The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α(1)-acid glycoprotein (AGP) in AKI and its progression to CKD using AGP KO mice. P...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Watanabe, Hiroshi, Fujimura, Rui, Hiramoto, Yuto, Murata, Ryota, Nishida, Kento, Bi, Jing, Imafuku, Tadashi, Komori, Hisakazu, Maeda, Hitoshi, Mukunoki, Ayumi, Takeo, Toru, Nakagata, Naomi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041882/
https://ncbi.nlm.nih.gov/pubmed/33846468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87217-8
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