A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein

Renal fibrosis is a major factor in the progression of chronic kidney disease and the final common pathway of kidney injury. Therefore, the effective therapies against renal fibrosis are urgently needed. The objective of this study was to investigate the effect of Am80, a synthetic retinoic acid rec...

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Published in:Sci Rep
Main Authors: Watanabe, Hiroshi, Bi, Jing, Murata, Ryota, Fujimura, Rui, Nishida, Kento, Imafuku, Tadashi, Nakamura, Yuka, Maeda, Hitoshi, Mukunoki, Ayumi, Takeo, Toru, Nakagata, Naomi, Kurauchi, Yuki, Katsuki, Hiroshi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351735/
https://ncbi.nlm.nih.gov/pubmed/32651445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68337-z
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