Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition

BACKGROUND: Inhibition of acetylcholinesterase (AChE), a biomarker of organophosphorous and carbamate exposure in environmental and occupational human health, has been commonly used to identify potential safety liabilities. So far, many environmental chemicals, including drug candidates, food additi...

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Vydáno v:Environ Health Perspect
Hlavní autoři: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Travers, Jameson, Klumpp-Thomas, Carleen, Yu, Wenbo, MacKerell, Alexander D., Sakamuru, Srilatha, Ooka, Masato, Xue, Fengtian, Sipes, Nisha S., Hsieh, Jui-Hua, Ryan, Kristen, Simeonov, Anton, Santillo, Michael F., Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: Environmental Health Perspectives 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041433/
https://ncbi.nlm.nih.gov/pubmed/33844597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP6993
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