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Expanding biological space coverage enhances the prediction of drug adverse effects in human using in vitro activity profiles
In vitro assay data have recently emerged as a potential alternative to traditional animal toxicity studies to aid in the prediction of adverse effects of chemicals on humans. Here we evaluate the data generated from a battery of quantitative high-throughput screening (qHTS) assays applied to a larg...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830476/ https://ncbi.nlm.nih.gov/pubmed/29491351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22046-w |
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